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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC6L
All Species:
7.88
Human Site:
S1118
Identified Species:
24.76
UniProt:
Q2NKX8
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2NKX8
NP_060139.2
1250
141103
S1118
E
E
R
L
D
D
S
S
E
A
K
G
P
E
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092609
1252
141491
S1122
E
E
R
L
D
D
S
S
E
A
K
G
A
E
D
Dog
Lupus familis
XP_549075
1268
143171
S1136
M
E
E
G
P
D
N
S
S
K
A
E
V
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHK9
1240
138836
D1109
E
D
M
E
E
R
L
D
N
S
S
E
E
E
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505482
1393
155753
E1121
E
E
A
E
E
G
S
E
E
T
G
D
S
E
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2BGR3
1451
163208
E1320
D
E
S
V
V
E
E
E
E
P
S
G
E
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P41877
1009
116656
R892
K
A
P
F
Q
Q
L
R
I
S
Y
G
T
N
K
Sea Urchin
Strong. purpuratus
XP_781405
563
63991
S446
Y
D
E
N
D
D
P
S
E
M
E
C
A
A
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.5
78.8
N.A.
73.4
N.A.
N.A.
49.9
N.A.
N.A.
44.4
N.A.
N.A.
N.A.
24.7
22.9
Protein Similarity:
100
N.A.
98.4
85.8
N.A.
82.3
N.A.
N.A.
63.8
N.A.
N.A.
60
N.A.
N.A.
N.A.
42.7
33.2
P-Site Identity:
100
N.A.
93.3
20
N.A.
13.3
N.A.
N.A.
33.3
N.A.
N.A.
20
N.A.
N.A.
N.A.
6.6
26.6
P-Site Similarity:
100
N.A.
93.3
33.3
N.A.
33.3
N.A.
N.A.
46.6
N.A.
N.A.
40
N.A.
N.A.
N.A.
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
13
0
0
0
0
0
0
25
13
0
25
25
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% C
% Asp:
13
25
0
0
38
50
0
13
0
0
0
13
0
0
25
% D
% Glu:
50
63
25
25
25
13
13
25
63
0
13
25
25
50
25
% E
% Phe:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
13
0
13
0
0
0
0
13
50
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% I
% Lys:
13
0
0
0
0
0
0
0
0
13
25
0
0
0
13
% K
% Leu:
0
0
0
25
0
0
25
0
0
0
0
0
0
0
13
% L
% Met:
13
0
13
0
0
0
0
0
0
13
0
0
0
0
0
% M
% Asn:
0
0
0
13
0
0
13
0
13
0
0
0
0
13
13
% N
% Pro:
0
0
13
0
13
0
13
0
0
13
0
0
13
0
0
% P
% Gln:
0
0
0
0
13
13
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
25
0
0
13
0
13
0
0
0
0
0
0
0
% R
% Ser:
0
0
13
0
0
0
38
50
13
25
25
0
13
0
13
% S
% Thr:
0
0
0
0
0
0
0
0
0
13
0
0
13
13
0
% T
% Val:
0
0
0
13
13
0
0
0
0
0
0
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _